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AS & A Level · AS/A Level

Biology

Cells and microscopy

Name: ____________________Date: October 10, 2026
  1. 1.

    Explain how rough endoplasmic reticulum and the Golgi apparatus cooperate in secretion of a protein.

    [3 marks] · no calculator
  2. 2.

    Distinguish magnification from resolution in microscopy and explain why enlarging a blurred image need not reveal two adjacent structures.

    [3 marks] · no calculator
  3. 3.

    A cell appears 36 mm long at magnification x1200. Calculate its actual length in micrometres.

    [3 marks]
  4. 4.

    A micrograph shows circular profiles of mitochondria. Explain why this does not establish that the intact mitochondria are spherical.

    [3 marks] · no calculator
  5. 5.

    During cell fractionation, explain why tissue is homogenised in cold, isotonic, buffered solution before differential centrifugation.

    [4 marks] · no calculator
  6. 6.

    A cell image is enlarged digitally after a scale bar was added. Explain when the bar remains valid, why a printed magnification label may not, and how to check a measured cell length.

    [4 marks] · no calculator

Original, unofficial practice questions from SubjectScout — not official past-paper questions.

Marking points are indicative, not an official mark scheme. Accept equivalent valid methods and supported interpretations that address the task; award each mark once without requiring the model wording.